Focus on Ingredients: AiE/10 for Immune Support

Many substances are known to affect the structure and function of the immune system; some are mere stimulants, while others modulate immune function. The nutritional ingredient Ai/E10®, has been studied for its ability to stimulate restoration and maintenance of immune function, resulting in improved immune competence and balance.

Ai/E10 can be used as an ingredient in food, as a dietary supplement, or as an inactive ingredient in homeopathic remedies and drug products; it has been self-affirmed GRAS (generally recognized as safe).

Ai/E10 is a patented and proprietary ingredient for the immune system. Ai/E10 is a refined lacteal peptide complex that consists of over 60 hyper-immunized communication molecules to help the immune system recognize, respond to, and remember germs that come into the body. This unique ingredient can be found in the HealthPro Nutrient products Cell Balance and Cell Design.

 
Studies:
The following studies utilizing Ai/E10 were conducted by Solstice Clinical Associates, Tucson, AZ; Quantum Research Inc., Scottsdale, AZ; Immune Consultants, Tucson, AZ:

Study 1:

• 107 patients with documented and advanced chronic illness
• Followed and treated with Ai/E10 for 13.2 months
• Natrual Killer (NK) cell activity rose significantly, placing them at the high end of the recognized range for people in a healthy population (246 Lytic Units [LU])
  

Study 2:

• 12 healthy adults 
• Monitored over 90 days as they 
• Consumed 100 mg of Ai/E10 daily 
• Intervention significantly elevated NK cell activity from a pre-study mean of 30 LU to a post-study mean of 101 LU. 
• Additionally, Ai/E10 consumption significantly reduced “symptoms” on a general health evaluation.

Study 3:

• Monitored the activity of NK cells, macrophages, and Tumor Necrosis Factor (TNF) activity
• 20 participants; 10 received a placebo; 10 took 200 mg of Ai/E10 daily for 15 days. 
• The study group exhibited a clear “modulated” immune response, elevating key immune markers occurring in concert with each other, which is consistent with observations of the immune system’s ability to recognize and respond.

Berlett Dietary Ingredients also conducted a study on Ai/E10, the results of which were published in the Townsend Letter, Examiner of Alternative Medicine, in December 2006. Ai/E10 was compared to other substances marketed for immune support, including colostrum, maitake, arabinogalactan, lactoferrin and astragalus. The researchers reported all materials demonstrated immune stimulation; however Ai/E10 also had a strong, reliable capability to increase immune surveillance and transfer immunological information among cell groups.



This posting is based on an article originally published by David L. Bergsma in Natural Products Insider, August 2008