Breaking News on Supplements & Nutrition - North America
Researchers at the Chicago based Rush University Medical Center has received $750,000 in funding from the US Department of Defense to study microbial cells in the human gut and the mechanism by which they can influence health and disease.
The researchers, led by gastroenterologist Dr. Ece Mutlu, said that they hoped to determine whether gastrointestinal microbiota has the potential to explain rises in breast cancer incidence.
The study is part of a wider project aimed at understanding how changes in bacterial genomes, known as the human microbiome, can be correlated with changes in human health, according to the Medical Center.
The researchers want to map out the composition of gut microorganisms and they hypothesize that if they are able to find the microbes responsible for certain diseases it could influence potential treatments or diagnostic tools.
Breast cancer susceptibility genes explain less that five to 10 per cent of total breast cancer cases related to familiar factors, maintain the research team.
Moreover, they claim that the gut microbiome passed on from mother to child may be another familiar factor previously never taken into account in the genetic risk models for the disease.
The team said that they will use a technology for genomic sequencing called Multitag Pyrosequencing (MTPS) that will allow them to identify 50,000 or 60,000 microbes per sample.
The team said they are currently recruiting study participants who are female, 30 years of age or older, and newly diagnosed with breast cancer before any treatment has begun.
Clinical data from the participant’s medical records will be taken, and prior to a patient receiving any cancer-related therapy, biopsies of the colon and stool specimens will be taken, added the researchers.
The researchers, led by gastroenterologist Dr. Ece Mutlu, said that they hoped to determine whether gastrointestinal microbiota has the potential to explain rises in breast cancer incidence.
The study is part of a wider project aimed at understanding how changes in bacterial genomes, known as the human microbiome, can be correlated with changes in human health, according to the Medical Center.
The researchers want to map out the composition of gut microorganisms and they hypothesize that if they are able to find the microbes responsible for certain diseases it could influence potential treatments or diagnostic tools.
Breast cancer susceptibility genes explain less that five to 10 per cent of total breast cancer cases related to familiar factors, maintain the research team.
Moreover, they claim that the gut microbiome passed on from mother to child may be another familiar factor previously never taken into account in the genetic risk models for the disease.
The team said that they will use a technology for genomic sequencing called Multitag Pyrosequencing (MTPS) that will allow them to identify 50,000 or 60,000 microbes per sample.
The team said they are currently recruiting study participants who are female, 30 years of age or older, and newly diagnosed with breast cancer before any treatment has begun.
Clinical data from the participant’s medical records will be taken, and prior to a patient receiving any cancer-related therapy, biopsies of the colon and stool specimens will be taken, added the researchers.
Source: Jane Byrne, Nutra-Ingredients.com
No comments:
Post a Comment